Fig. 9.

Effects of DRB and DMAT on STAT1 serine 727 phosphorylation. INS-1E cells were cultured for 30 min or 2 h in the absence or presence of cytokines (IL-1β, TNF-α, and IFN-γ) (3mix) and DRB (50 μM) (DRB₅₀) or DMAT (5 μM) (DMAT₅) as indicated before determination of STAT1 phosphoserine 727 (pSTAT1_ser727). Results are mean ± SEM (n = 3–5) with a representative experiment shown below bars. a *P < 0.01 versus 3mix; b *P < 0.001 versus 3mix