Table 5.
Functional profiles in subjects with euthyroidism and subclinical hypothyroidism, by age group
| Variable | <85 years | ≥85 years | ||
|---|---|---|---|---|
| Thyroid status | Euthyroidism | Subclinical hypothyroidism | Euthyroidism | Subclinical hypothyroidism |
| n | 174 | 29 | 61 | 14 |
| Katz Index | 1.00 ± 1.5 (0.0) | 1.4 ± 1.7 (1.0) | 1.7 ± 1.7 (1.0)* | 0.9 ± 1.6 (0.5)* |
| Functional dependence, Katz Index (%) | 49.4 | 65.5 | 80.3† | 50.0† |
| HAQ | 1.2 ± 0.9 (1.1) | 1.5 ± 1.0 (1.5) | 1.8 ± 0.8 (1.9)** | 1.2 ± 0.8 (0.9)** |
| Functional dependence, HAQ (%) | 44.8 | 62.1 | 78.7α | 35.7α |
| Recurrent falls (%)a | 11.0 | 10.3 | 13.6 | 7.1 |
| Medications used | 6.5 ± 2.7 (6.0) | 7.4 ± 2.6 (7.0) | 6.4 ± 2.9 (6.0) | 5.4 ± 2.6 (5.5) |
| Cognitive deficit (%) | 48.6 | 51.7 | 70.0 | 78.6 |
| Heart failure | 29.7 | 39.3 | 41.7 | 29.0 |
| Coronary artery disease | 8.1 | 3.6 | 13.3 | 0.0 |
| Cerebrovascular disease | 15.1 | 28.6 | 18.3 | 7.1 |
| Depressive disorder (%) | 44.4 | 42.9 | 49.1 | 71.4 |
Continuous variables are presented as mean ± standard deviation (median)
SHypo subclinical hypothyroidism, HAQ health assessment questionnaire
* p = 0.024; ** p = 0.015; † p = 0.036; α p = 0.004
a Three or more falls in the last year