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. 2014 Jul 28;12(8):4291–4310. doi: 10.3390/md12084291

Figure 1.

Figure 1

The mortality, brain water content and Evans blue extravasation among each group. (A) No rats died in the sham group (zero of 30 rats); eight of 38 rats died in the SAH group, seven of 37 in the SAH + vehicle group and four of 34 in the SAH + ATX group. No significant differences were observed in mortality among each group; (B) The brain water content was increased significantly at 24 h after SAH. ATX treatment post-SAH could significantly reduce brain water content when compared with that in the SAH + vehicle group; (C) Compared with the sham group, SAH lead to a significant increase in Evans blue extravasation. After ATX administration, the increased blood-brain barrier (BBB) extravasation was markedly reduced as compared with the SAH + vehicle group. Values are expressed as means ± SEM. ** p < 0.01, * p < 0.05, ns p > 0.05.