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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: ChemMedChem. 2014 Mar 5;9(7):1368–1373. doi: 10.1002/cmdc.201300506

Table 1.

Observed and second order rate constants for the acid-catalyzed 18F/19F exchange of BFL-NHS (2)

mM kobs (10−4) ±3σ (10−4) % Error
Tf2O/tBuOH 40 7.95 1.01 12.7
14 4.16 0.26 6.3
10 3.09 0.26 8.5
BFL-NHS (2) 2.0 7.95 1.01 12.7
1.0 3.98 0.40 10.0
0.5 2.32 0.16 7.0
k (10−4 M−1 s−1) Error (10−4)
Tf2O/tBuOH 0.69 0.10
BFL-NHS (2) 4.19 0.15