Table 2.
Entry | BODIPY Dye | 18F− Incorporation (%) | Specific Activity (mCi/μmol) |
---|---|---|---|
1 | B493-NHS | 90.6 | 12.8 |
2 | BFL-NHS | 63.8 | 6.5 |
3 | B530-NHS | 16.2 | 1.9 |
4 | BTMR-X-NHS | 65.1 | 8.5 |
5 | B630-X-NHS | 24.3 | 2.6 |
6 | BFL-Mal | 60.4 | 4.0 |
After 30 min reaction time at 50 °C (2.5 μmol Tf2O/tBuOH, 125 nmol BODIPY), yields determined by HPLC (Method C).