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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: ChemMedChem. 2014 Mar 5;9(7):1368–1373. doi: 10.1002/cmdc.201300506

Table 2.

Radiochemical yields and specific activity of 18F/19F exchange of 6 commercially available BODIPY fluorophores.a

Entry BODIPY Dye 18F Incorporation (%) Specific Activity (mCi/μmol)
1 B493-NHS 90.6 12.8
2 BFL-NHS 63.8 6.5
3 B530-NHS 16.2 1.9
4 BTMR-X-NHS 65.1 8.5
5 B630-X-NHS 24.3 2.6
6 BFL-Mal 60.4 4.0
a

After 30 min reaction time at 50 °C (2.5 μmol Tf2O/tBuOH, 125 nmol BODIPY), yields determined by HPLC (Method C).