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Association of PADI4 SNP (recessive model) with Sharp/van der Heijde score of hands at 5-year disease duration in ACPA-negative RA patients
| Factor | Beta (95% CI) | P value |
|---|---|---|
| rs2240340, PADI4 | 0.72 (0.08-1.36) | 0.0287 |
| HLA-DRB1 SE | 0.36 (0.01-0.73) | 0.0587 |
| RF | 0.54 (0.05-1.02) | 0.0316 |
ACPA, Anti-citrullinated peptide antibody; CI, Confidence interval; PADI4, Peptidyl arginine deiminase type IV; RA, Rheumatoid arthritis; RF, Rheumatoid factor; SE, Shared epitope; SNP, Single-nucleotide polymorphism.
