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Insulin resistance in mice given a high-fat diet and low-dose streptozotocin injection: (a) IPGTT data: glucose tolerance test data from control and high-fat/low-dose STZ (HFD + LDS) groups. Blood glucose was measured after 60, 90, and 120 min of 2 g/kg d-glucose intraperitoneal injection. ***P < 0.0001; n = 4 mice from each group. (b) Plasma insulin levels: plasma was isolated from blood collected at the end of the protocol. NS, non significant; n = 5 mice from each group
