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. Author manuscript; available in PMC: 2015 Aug 1.
Published in final edited form as: J Thorac Oncol. 2014 Aug;9(8):1101–1110. doi: 10.1097/JTO.0000000000000214

Figure 1. A&B. CD46 expression on NSCLC cells.

Figure 1

A) Plot of fluorescence intensity (relative to isotype) of cells stained with phycoerythrin-labeled anti-CD46 and assessed by flow cytometry. B) Representative histograms. LLC = murine Lewis Lung Carcinoma cell line as a negative control. C) Plot of fluorescence intensity (relative to isotype) of cells stained with phycoerythrin-labeled anti-Nectin-4 and assessed by flow cytometry. D) Representative histograms. E) Light (LM-top) and fluorescence (FM-bottom) microscopy of H2009 cells infected with MV-GFP after treatment with blocking antibodies against CD-46 and Nectin-4 or the combination. F) Quantification of fluorescence after blocking CD-46 and Nectin-4. Isotype IgG and H2009 cells untreated with MV-GFP were used as positive and negative controls, respectively.