Table 2. Secondary Assay Results Summary for Six Representative Inhibitor Compounds.

^aThe ELISA IC₅₀ values were determined by performing the assay in duplicate for each compound, followed by normalization of data and subsequent data fitting in GraphPad with the aid of log(inhibitor) vs response (variable slope) plots and nonlinear regression fit.

^bThe degradation of p53, as determined by the in vitro experiments with both HPV 16 and HPV 18 E6, is reported as an approximate IC₅₀ over a concentration range.

^cThe thermal stability result is as described in the text.