Figure 4.

microRNA-1202 (miR-1202) identifies patients at high risk of inadequate response to left ventricular assist device (LVAD) support. We used change in change in NT-proBNP after 3 months of LVAD support as a marker of clinical response to LVAD support (n = 13). Dividing the cohort at the median identified good (n = 7) and poor (n = 6) responders. The scatterplot (A) and boxplot (B) show plasma miR-1202 expression before LVAD implantation, identifying good vs. poor responders. Expression of circulating miR-1202 varied significantly between these groups [good, 1.296 (1.293–1.306) vs. poor, 1.311 (1.310–1.318) AU; P = 0.004].