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. 2014 Aug 18;7:1455–1464. doi: 10.2147/OTT.S67057

Figure 7.

Figure 7

Slope values of BCSC proliferation rates and doubling times of BCSCs.

Notes: BCSC proliferation was inhibited after 24 hours’ incubation with DCs and CTLs, with decreased slope values and increased doubling times. Slope values and doubling times were also different in G4, G5, and G6 in which the ratios of DCs to CTLs differed. Groups: G1= BCSCs; G2= mature primed DCs; G3= induced T-cells; G4= BCSCs + mature primed DCs + induced T-cells (DCs:T-cells =1:10); G5= BCSCs + mature primed DCs + induced T-cells (DCs:T-cells =1:20); G6= BCSCs + mature primed DCs + induced T-cells (DCs:T-cells =1:40). A–D: Slope values (1/h) of BCSCs for 0-24 h, 24-48 h, 48-72 h, and 72-96 h, respectively. E–H: Doubling time (h) of BCSCs for 0-24 h, 24-48 h, 48-72 h, and 72-96 h, respectively.

Abbreviations: BCSC, breast cancer stem cell; CTL, cytotoxic T lymphocyte; DC, dendritic cell; h, hour.