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. 2014 Aug 19;7:1465–1472. doi: 10.2147/OTT.S66809

Table 1.

Correlations between B7-H1, B7-H3, and B7-H4 expressions and patient pathological parameters

Pathological parameters Cases B7-H1 expression
P-value B7-H3 expression
P-value B7-H4 expression
P-value
Low High Low High Low High
Sex
 Male 41 26 15 0.06 12 29 0.58 18 23 0.19
 Female 22 13 9 8 14 14 8
Age (years)
 ≥60 41 29 12 0.06 18 23 0.44 24 17 0.12
 <60 22 10 12 12 10 8 14
Location
 Head 35 21 14 0.91 14 21 0.29 20 15 0.1
 Body 13 8 5 3 10 8 5
 Tail 15 10 5 3 12 4 11
Tumor size (cm)
 ≤5 25 11 14 0.03 5 20 0.17 6 19 <0.01
 >5 38 28 10 15 23 26 12
Differentiation
 Low 36 21 15 0.75 10 26 0.05 18 18 0.83
 Moderate 22 15 7 6 16 12 10
 High 5 3 2 4 1 2 3
Tumor (T) statusa
 pT1 5 5 0 0.11 2 3 0.58 2 3 <0.01
 pT2 19 14 5 8 11 13 6
 pT3 25 13 12 7 18 16 9
 pT4 14 7 7 3 11 1 13
Nodal (N) statusb
 N0 26 16 10 1 13 13 0.01 18 8 0.02
 N1 37 23 14 7 30 14 23
Distant metastasis (M)c
 M0 33 23 10 0.21 9 24 0.59 20 13 0.13
 M1 30 16 14 11 19 12 18

Notes:

a

The depth of tumor invasion is classified as follows: pT1, invasion of lamina propria or submucosa; pT2, invasion of muscularis propria; pT3, invasion of adventitia; and pT4, invasion of adjacent structures

b

lymph-node metastasis is classified as follows: N0, no regional lymph-node metastasis; N1, regional lymph-node metastasis

c

distant metastasis is classified as follows: M0, no distant metastasis; M1, metastasis to cervical nodes, celiac nodes, and other distant metastases. P<0.05 was considered significant.