Voxel based morphometry analysis of patients with minimal hepatic encephalopathy and healthy controls. Minimal hepatic encephalopathy patients show grey matter volume losses in the frontal and temporal cortices, caudate, putamen, amygdale, paracentral lobule, anterior and middle cingulate cortices, supplementary motor area, and increased volume in the thalamus. From reference [6] (with permission). L: Left; R: Right.