Table 2.
Response rates in the subjects with irritable bowel syndrome-diarrhea for abdominal pain and diarrhea n (%)
| Arm | n | CR | PR | SR | NR | Response rate | |
| Abdominal pain | |||||||
| Per protocol | A | 82 | 22 (26.8) | 21 (25.6) | 27 (32.9) | 12 (14.6) | 43 (52.4)a |
| B | 88 | 14 (15.9) | 15 (17.0) | 28 (31.8) | 31 (35.2) | 29 (33.0) | |
| Intention-to-treat | A | 100 | 22 (22) | 21 (21) | 27 (27) | 30 (30) | 43 (43)a |
| B | 100 | 14 (14) | 15 (15) | 28 (28) | 43 (43) | 29 (29) | |
| Diarrhea | |||||||
| Per protocol | A | 82 | 25 (30.5) | 25 (30.5) | 23 (28) | 9 (11) | 50 (61.0)b |
| B | 88 | 13 (14.8) | 21 (23.9) | 30 (34.1) | 24 (27.3) | 34 (38.6) | |
| Intention-to-treat | A | 100 | 25 (25) | 25 (25) | 23 (23) | 27 (27) | 50 (50)a |
| B | 100 | 13 (13) | 21 (21) | 30 (30) | 36 (36) | 34 (34) | |
| Abdominal pain plus diarrhea | |||||||
| Per protocol | A | 82 | 24 (29.3) | 28 (34.1) | 21 (25.6) | 9 (11) | 52 (63.4)b |
| B | 88 | 11 (12.5) | 26 (29.5) | 15 (17.0) | 36 (40.9) | 37 (42.0) | |
| Intention-to-treat | A | 100 | 24 (24) | 28 (28) | 21 (21) | 27 (27) | 52 (52)a |
| B | 100 | 11 (11) | 26 (26) | 15 (15) | 48 (48) | 37 (37) | |
a
P < 0.05,
b
P < 0.01 vs arm B. CR: Complete response; NR: Non-response; PR: Partial response; SR: Slight response.