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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Biochem J. 2014 Sep 1;462(2):359–371. doi: 10.1042/BJ20140291

Table 1. Isolated mitochondrial respiration in heart and skeletal muscle from Surf1−/− and wild-type mice.

State 3, state 4, respiratory control ratio (RCR) and ADP to oxygen ratio (P:O) were measured in isolated heart or hind-limb skeletal muscle mitochondria. N=6–10 per experimental group, data are means ± SEM and significance determined by 2-tailed t-test.

Tissue Genotype State 3 State 4 RCR
(State3/State4)
ADP:O
Heart Wild-type 325±27 58±5 5.3±0.5 1.98±0.2
Surf1−/− 264±17 * 59±6 4.8±0.6 2.10±0.2
Skeletal Wild-type 548±58 53±3 10.5±1.3 3.38±0.4
Muscle Surf1−/− 527±44 52±3 10.7±1.6 2.93±0.4