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. 2014 Aug 18;9:3971–3985. doi: 10.2147/IJN.S67343

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© 2014 Li et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Tissue distribution of PTX in EMT6 tumor bearing mice attained at 1 hour (A), 8 hours (B), 12 hours (C), and 24 hours (D) after intravenous administration with different PTX formulations.

Notes: Values are represented as the mean ± SD (n=3). *P<0.05, **P<0.01. (E) Different coumarin 6 formulations displayed fluorescence in breast tumor tissues frozen slices 1 hour after administration. (F) Different coumarin 6 formulations displayed fluorescence in breast tumor tissues frozen slices 8 hours after administration. Representative images of tumor sections were at 200× magnification.

Abbreviations: DAPI, 4′,6-diamidino-2-phenylindole; PTX, paclitaxel; PTX-NPs, paclitaxel-lipid perfluorooctylbromide nanoparticles; PTX-SNPs, paclitaxel-sulfatide-containing lipid perfluorooctylbromide nanoparticles.