Figure 9.
Inhibition of angiogenesis assayed by immunohistochemistry.
Notes: Representative images (at 200× magnification) of tumor sections that were stained immunohistochemically with anti-CD31 antibody from mice treated with (A) saline, (B) blank SNPs, (C) Taxol, (D) PTX-NPs, and (E) PTX-SNPs are shown. (F) Quantitative assay of MVD from six random fields. The results are presented as the mean ± SD (n=6). *P<0.05. **P<0.01.
Abbreviations: MVD, microvessel density; PTX-NPs, paclitaxel-lipid perfluorooctylbromide nanoparticles; PTX-SNPs, paclitaxel-sulfatide-containing lipid perfluorooctylbromide nanoparticles; SD, standard deviation; SNPs, sulfatide-containing lipid perfluorooctylbromide nanoparticles.