Table 3.
Effect on hematology and liver function parameters in healthy BALB/c mice intravenously injected with saline and blank SNPs for 2 weeks
| Parameter | Saline | Blank SNPs |
|---|---|---|
| RBCs (×1012/L) | 8.29±0.89 | 8.25±0.82 |
| WBCs (×109/L) | 5.62±0.71 | 5.49±0.60 |
| PLTs (×109/L) | 945.8±166.88 | 1013.9±159.12 |
| Lymphocytes (%) | 65.8±6.00 | 65.4±5.82 |
| ALT (IU/L) | 46.2±5.6 | 43.1±5.4 |
| AST (IU/L) | 102±5.40 | 104±5.19 |
| T-Bil (μmol/L) | 1.02±0.074 | 1.01±0.063 |
Notes: Data were presented as mean ± SD (n=10). There was no significant difference of the above parameters compared with the saline group (P>0.05).
Abbreviations: ALT, alanine transaminase; AST, aspartate transaminase; PLTs, platelets; RBCs, red blood cells; SD, standard deviation; SNPs, sulfatide-containing lipid perfluorooctylbromide nanoparticles; T-Bil, total bilirubin; WBCs, white blood cells.