TABLE II.
RT-PCR AND IMMUNOHISTOCHEMISTRY (IH) SUMMARY
| Tumors | RT-PCR1 | Aberrant product | IH score2 |
|---|---|---|---|
| #CA2 | N and aberrant | Exon 6–8 deletion Exon 7 deletion |
+2 |
| #CA3 | A | – | +1 |
| #CA4 | N | – | +3 |
| #CA5 | Aberrant | Exon 6–8 deletion | +1 |
| #CA7 | N | – | +3 |
| #CA8 | N | – | +3 |
| #CA9 | N | – | +3 |
| #CA10 | N | – | +2 |
| #CA11 | N | – | +2 |
| #CA12 | N and aberrant | Exon 8–9 deletion3 | +2 |
| #CA13 | N | – | +3 |
| #CA14 | N | – | +3 |
| #CA16 | N | – | +1 |
| #CA17 | N | – | +3 |
| #CA18 | A | – | +2 |
| #CA19 | N | – | +3 |
| #CA20 | N | – | +3 |
| #CA21 | N and aberrant | Exon 6–8 deletion | +3 |
| #CA22 | N | – | +3 |
| #CA24 | N and aberrant | Exon 6–8 deletion | +3 |
1
RT-PCR: N, wild type transcript; A, absence of transcript.
2
Immu-nohistochemistry scores; +1, 0–10% positive cells; +2, 11–50% positive cells; +3, >51% positive cells. Normal mucosas were used as positive controls, all score +3.
3
Partial exon deletion.