FIGURE 6:
Changes in eGFR(Eqcr) slope (A), TKV slope (B) and %TKV slope (C) between pre-study and during water study periods. The slopes in the pre-study period were calculated from 2 to 3 years of observation and those during the water study from 1-year observation. The lines connect individual data and unconnected single points correspond to the participants without pre-study data. Single data were input to draw the figure but only paired data were used for statistical calculation. Horizontal bar represents the mean. After increasing water intake in the high water-intake group, eGFR(Eqcr) slope (A) became more negative (from −0.3 ± 3.0 to −7.1 ± 8.6) and TKV slope (B) became more positive (from 72 ± 89 to 149 ± 113). The %TKV slope (C) also increased (from 3.8 ± 5.7 to 9.1 ± 6.3) in the high water-intake group, but the changes did not reach statistical significance. (The data in parentheses are the means ± SD of paired data.)