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. 2013 Apr 5;8(10):900–908. doi: 10.3969/j.issn.1673-5374.2013.10.004

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of minocycline on poly(adenosine diphosphate-ribose) polymerase-1 expression in the hippocampal CA1 region of rats after cerebral ischemia-reperfusion (I/R) (immunohistochemical staining, × 200).

Poly(adenosine diphosphate-ribose) polymerase-1-positive cells were not observed in the sham-operation group; changes in the number of poly(adenosine diphosphate-ribose) polymerase-1-positive cells in the I/R group; the number of poly(adenosine diphosphate-ribose) polymerase-1-positive cells in the minocycline group were significantly less than in the I/R group. Arrows point to poly(adenosine diphosphate-ribose) polymerase-1-postive cells.