Figure 2.

Effects of ursolic acid on S100 mRNA expression in L_4–6 spinal segments of mice following sciatic nerve injury (real-time quantitative PCR).

Data (fluorescent density [dRn] of S100 to GAPDH) are expressed as mean ± SD, and there were five mice in each group at each time point. Mice in high-, medium-, and low-dose ursolic acid groups were intraperitoneally injected with 10, 5, 2.5 mg/kg ursolic acid. ^aP < 0.05, vs. model group; ^bP < 0.05, vs. low-dose ursolic acid group; ^cP < 0.05, vs. medium-dose ursolic acid group (pairwise comparisons were performed using Duncan's method).