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Cell proliferation after treatment with different concentrations of alpha-synuclein.
(A) Control, (B) alpha-synuclein 50 nmol/L, (C) alpha-synuclein 100 nmol/L, (D) alpha-synuclein 1 μmol/L. 4’,6-Diamidino-2-phenylindole (DAPI) staining (blue), 5-bromo-2’-deoxyuridine (BrdU) staining (red), × 100. Proportion of BrdU-positive cells was decreased after 24 hour alpha-synuclein treatment in neuronally-differentiated SH-SY5Y cells.
