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. 2013 Jun 15;8(17):1551–1559. doi: 10.3969/j.issn.1673-5374.2013.17.002

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of cochlear microinjection of recombinant lentivirus carrying extrinsic Atoh1 on rat cochlear hair cells (propidium iodide staining).

Three rows of OHCs (OHC1, OHC2, OHC3) showed no differences. Arrows indicate dispersive loss of OHCs or IHCs. There was no significant difference in the numbers of hair cells among different groups. Scale bars: 2.5 μm.

(A) Lentivirus-enhanced green fluorescent protein-Atoh1 microinjection group; (B) lentivirus-enhanced green fluorescent protein microinjection group; (C) artificial perilymph injection group; (D) non-injection group.

OHC: Outer hair cell; IHC: inner hair cell.