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. 2013 Aug 25;8(24):2236–2248. doi: 10.3969/j.issn.1673-5374.2013.24.003

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of combined GDAs^BMP and hr-decorin transplantation on the cross-sectional area in the contused spinal cord of rats.

The cross-sectional area of the spinal cord in the glial fibrillary acidic protein-positive astrocyte fluorescence image was measured and analyzed with Image Pro Plus 6.0 software, and calculated by pixels. The cross-sectional area of combined GDAs^BMP and hr-decorin transplantation group was least at 7 and 28 days (^aP < 0.05, vs. the other groups at the same time); the cross-sectional area of hr-decorin group and GDAs^BMP transplantation group was always larger than the blank group (^bP < 0.05). Data are expressed as mean ± SD of six rats for each group (two-sample t-test and one-way analysis of variance).

Blank: Spinal cord injury group; Hr-decorin: human recombinant decorin injection group; GDAs^BMP: glial-restricted precursor-derived astrocytes induced by bone morphogenetic protein-4 transplantation group; GDAs^BMP + Hr-decorin: combined GDAs^BMP and hr-decorin transplantation group.