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. 2013 Aug 5;8(22):2069–2077. doi: 10.3969/j.issn.1673-5374.2013.22.006

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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The effect of electroacupuncture at He-Mu points on P2X4 receptor immunoreactivity in the spinal cord of rats with chronic visceral hypersensitivity.

(A) Immunohistochemistry for P2X4 receptor immunoreactivity in the rat spinal cord (× 400). (A1-4) Control, model, electroacupuncture and pinaverium bromide groups, respectively. P2X₄ receptor immunoreactivity was increased in the model group, but significantly reduced in the electroacupuncture and pinaverium bromide groups. Arrows show P2X₄ receptor immunoreactivity. (B) Semiquantitative analysis of P2X₄ receptor immunoreactivity. Data are expressed as mean ± SD. Intergroup comparison was performed using the least significant difference t-test. ^aP < 0.01, vs. control group; ^bP < 0.01, vs. model group.