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. 2013 Mar 15;8(8):693–701. doi: 10.3969/j.issn.1673-5374.2013.08.003

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effects of treatment with tadalafil on dopamine D₂ receptor expression in the striatum (A) and substantia nigra (B) following cerebral ischemia.

I: Sham-operation group; II: cerebral ischemia-induced group; III–V: 0.1, 1, and 10 mg/kg tadalafil-treated group, respectively.

One-way analysis of variance followed by Duncan's post-hoc test was used in performance of statistical analysis, and the results are presented as mean ± SEM of eight gerbils per group. The results are expressed as relative absorbance value of dopamine D₂ receptor/beta-actin normalized to sham-operation group. Each experiment was performed in triplicate. ^aP < 0.05, vs. sham-operation group; ^bP < 0.05, vs. cerebral ischemia- induced group.