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. 2013 Dec 5;8(34):3173–3182. doi: 10.3969/j.issn.1673-5374.2013.34.001

Figure 4.

Figure 4

Effects of lithium chloride on the activities of glycogen synthase kinase 3 beta (GSK-3β) and protein phosphatase 2A (PP2A) and the interaction between tau, GSK-3β and PP2A during brain ischemia and reperfusion.

(A) Western blot assay of the protein levels of p-GSK-3β and p-PP2A in rat hippocampus. (B) Immunoprecipitation analysis of the interaction between tau, GSK-3β and PP2A. Data are expressed as mean ± SD from eight rats at each time point. aP < 0.05, vs. sham-operated group; bP < 0.05, vs. 15-minute ischemia group; cP < 0.05, vs. 30 minute I/R group. I: Ischemia; R: reperfusion; WB: western blot; IP: immunoprecipitation; min: minute; h: hour.