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. 2014 Feb 15;9(4):343–355. doi: 10.4103/1673-5374.128235

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Structural components of chondroitin sulfate and heparan sulfate glycosaminoglycans.

Structural components of chondroitin sulfate and heparan sulfate glycosaminoglycans. (A) Chondroitin sulfate chains are comprised of repeat-ing disaccharide units of N-acetylgalactosamine (GalNAc) and glucuronic acid. GalNAc is either not sulfated, or sulfated at the 4, 6 or both 4 and 6 carbon positions. (B) These chains are arranged by the formation of a 1,4-β-glycosidic linkage. (C) Heparan sulfated chains are comprised of repeating disaccharide units of N-acetylglucosamine (GlcNAc) and glucuronic acid (GlcA). GlcNAc is either not sulfated, or sulfated at the 3 or 6 carbon position. GlcA may be sulfated at the 2 carbon position. (D) Like chondroitin sulfate these disaccharides are linked through a 1,4-β-glyco-sidic linkage. The chemical structures in were produced using Marvin Sketch Version 6.1.0, which was used under the ChemAxon Ltd. free educational license.