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. 2014 Mar 15;9(6):646–652. doi: 10.4103/1673-5374.130112

Figure 2.

Figure 2

Effect of glucocorticoids and RU-486 on serotonin transporter (SERT) activity.

Response curves of Ringer control, cortisol, dexamethasone, corticos-terone, and glucocorticoid receptor antagonist, mifepristone (RU-486) (10 μmol/L) in 100 μmol/L serotonin (5-HT) activated SERT channels, after the serotonin response reached a steady-state plateau. Each exper-iment was repeated six times. Sweeps 1–5: 100 μmol/L 5-HT + control, cortisol, dexamethasome, corticosterone, or RU-486.