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. 2014 Mar 15;9(6):602–609. doi: 10.4103/1673-5374.130101

Figure 5.

Figure 5

Effect of ERK1/2, P-ERK1/2 and GAP-43 expression in Schwann cells after treatment with FK506/RAPA.

(A) Western blot assay of ERK, p-ERK and GAP-43 in Schwann cells treated by FK506 (1.53 nM, 100 μM) and RAPA (25 μM, 1.53 nM). GAPDH was used as a loading control. (B–D) ERK, p-ERK and GAP-43 expression in Schwann cells treated with FK506 and RAPA. Data are expressed as mean ± SEM and are compared by one-way analysis of variance and Fisher's post hoc test. Each experiment was performed in triplicate. aP < 0.05, vs. control group; bP < 0.05, vs. RAPA 1.53 nM group. M: mol/L; ERK: extracellular signal-regulated kinase; p-ERK: phosphorylated ERK; GAP-43: growth-associated protein 43; RAPA: rapamycin.