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. 2014 May 15;9(10):1031–1040. doi: 10.4103/1673-5374.133164

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Microarray and bioinformatic analysis.

(A) Following sciatic nerve transection, the expression of 23 miRs was significantly changed in injured dorsal root ganglia versus control dorsal root ganglia. These miRs had expression levels greater than or equal to a 1.5-fold change (increase or decrease) in expression. (B) Potential targets of miR-214 were significantly enriched in the axon guidance pathway. (C) MiR-214 targets the 3’-UTR of srGAP3. miRs: MicroRNAs; srGAP3: Slit-Robo GTPase-activating protein 3.