Figure 2.
Effect of Dab2 overexpression on hippocampal transforming growth factor-β1 (TGF-β1)/SMAD signaling in Alzheimer's disease mice.
(A) Western blot analysis of hippocampal TβRII and phosphorylated SMAD2/3 levels. (B–D) Hippocampal TβRII and phosphorylated SMAD2/3 levels were significantly higher in the Dab2 group than in the vector group. One-way analysis of variance and the SNK-q test were used to assess the significance of differences between groups. Data are represented as mean ± SEM from at least three independent experiments. TβRII: TGF-β II receptor.