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. 2014 Jan 1;9(1):41–50. doi: 10.4103/1673-5374.125328

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Copyright: © Neural Regeneration Research

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of Dab2 overexpression on the learning and memory abilities of Alzheimer's disease (AD) mice as shown by the Morris water maze test.

(A, B) The escape latency and swimming distance of mice in the Dab2 group were significantly shorter than those of mice in the vector group (^aP < 0.05). (C) After removal of the platform, the percentage of time that mice spent in quadrant A was significantly higher in the Dab2 group than in the vector group (^aP < 0.05). One-way analysis of variance and the SNK-q test were used to assess the significance of differences between groups. Data are represented as mean ± SEM from at least three independent experiments.