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Changes in cytokine levels in MRL-lpr/lpr mice with or without irradiation.
| Authors of referenced studies lpr/lpr group | Cytokines | Non-irradiated MRL-lpr/lpr group versus normal group | Irradiated MRL-lpr/lpr group versus non-irradiated MRL- |
|---|---|---|---|
| Tanaka et al. 2005 | IFN-γ | ↓ | ↓ |
| IL-4 | ↓ | → | |
| IL-5 | ↓ | ↑ | |
| IL-12 | ↓ | ↓ |
↑ : significantly increased
↓ : significantly decreased
→ : not significantly different (same level).
