Table 1.
Mean (Standard Deviation) of Demographics, Disease Characteristics, and Behavioral Measures for the Negative, Low, Medium, and High Groups
| NEG n=16 | LOW n=16 | MED n=16 | HIGH n=16 | p | Post hocs | |
|---|---|---|---|---|---|---|
| Demographics | ||||||
| Age (years) | 42.9 (9.2) | 32.9 (9.2) | 39.9 (9.7) | 47.6 (12.6) | 0.002 | Low<Neg, High |
| Education (years) | 16.0 (1.9) | 14.4 (2.2) | 15.3 (2.5) | 13.9 (2.4) | 0.047 | High<Neg |
| Sex (% male) | 4 (25) | 1 (6.3) | 5 (31.3) | 2 (12.5) | 0.251 | |
| Location scanned (CC/UI) | 4/12 | 7/9 | 10/6 | 7/9 | 0.206 | |
| Disease characteristics | ||||||
| CAG | — | 41.8 (1.9) | 42.6 (2.6) | 43.6 (3.2) | 0.138 | |
| CAP score | — | 251.9 (30.2) | 332.3 (18.5) | 439.0 (45.5) | <0.001 | Low<Med<High |
| UHDRS motor score | 5.1 (4.5) | 3.5 (3.8) | 4.9 (4.4) | 13.4 (7.8) | <0.001 | Neg, Low, Med<High |
| Behavioral measures | ||||||
| SDMT | 61.0 (9.8) | 56.4 (10.4) | 56.8 (9.7) | 47.8 (10.6) | 0.002 | High<Neg, Med |
| Stroop color | 88.2 (15.10) | 84.4 (10.6) | 83.1 (10.6) | 68.9 (14.2) | <0.001 | High<Neg, Low, Med |
| Stroop word | 110.3 (19.8) | 107.1 (12.4) | 105.8 (16.1) | 84.4 (19.7) | <0.001 | High<Neg, Low, Med |
| Stroop interference | 51.4 (9.8) | 51.4 (12.8) | 52.4 (11.2) | 40.2 (10.6) | 0.006 | High<Neg, Low, Med |
| Trails A | 19.6 (4.3) | 23.7 (7.9) | 21.4 (8.7) | 30.3 (13.1) | 0.008 | Neg, Med<High |
| Trails B | 51.3 (19.0) | 50.8 (18.9) | 44.3 (8.7) | 83.7 (42.5) | <0.001 | Neg, Low, Med<High |
| Trails B-A | 31.3 (17.8) | 27.1 (15.8) | 22.8 (9.2) | 53.4 (38.3) | <0.001 | Neg, Low, Med<High |
| TRT: precision | 0.024 (0.005) | 0.020 (0.004) | 0.020 (0.006) | 0.019 (0.006) | 0.011 | High<Neg |
CAG, cytosine-adenine-guanine; CAP, CAG-age product; CC/UI, Cleveland Clinic/University of Iowa; SDMT, Symbol Digit Modalities Task; TRT, time reproduction task; UHDRS; Unified Huntington's Disease Rating Scale.