Figure 3. Helical wheel diagrams of Aedesin.

(A) N-terminal helix region (helix 1) from Lys³⁰ to Lys⁴⁸ and (B) C-terminal helix (helix 2) from Val⁵² to Ile⁵⁹. The hydrophobic or charged residues are indicated in black letters within the white circles and white letters within the dark grey circles, respectively. Other residues, including non-polar amino acids, are indicated in the light grey circles.