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. 2014 Aug 27;9(8):e105994. doi: 10.1371/journal.pone.0105994

Figure 1. Prx1 knockdown increases hypoxia and intracellular ROS production in SCC15 cells.

Figure 1

A, Prx1 protein was significantly decreased by shRNA transfection. B, Prx1 mRNA was significantly reduced by shRNA transfection. C, Pimonidazole staining showed the increased hypoxia status in cells after hypoxia/reoxygenation treatment. D, Intercellular ROS level identified by flow cytometry in cells after hypoxia/reoxygenation treatment. *P<0.05 vs. WT SCC15 cells; # P<0.05 vs. control hypoxic WT SCC15 cells.