Table 2. Incidence density (95% CI)a for coronary heart disease regarding risk factors at baseline.
Risk factorb | Risk factor – | Risk factor + | P-Valuec |
Men | |||
High risk age | 4.2 (3.2–5.4) | 19.5 (17.3–22.0) | <0.001 |
Family history of cardiovascular diseases | 11.4 (10.2–12.9) | 14.5 (11.1–18.9) | 0.107 |
Smoking | 10.4 (8.9–12.2) | 13.7 (11.7–15.9) | 0.012 |
Hypertension | 8.8 (7.6–10.1) | 23.2 (19.6–27.5) | <0.001 |
Diabetes Mellitus | 9.6 (8.4–10.9) | 31.4 (25.5–38.7) | <0.001 |
High total cholesterol | 9.7 (8.5–11.1) | 19.5 (16.2–23.4) | <0.001 |
Low HDL cholesterol | 10.9 (9.0–13.3) | 12.4 (10.8–14.1) | 0.283 |
Women | |||
High risk age | 3.3 (2.7–4.0) | 16.4 (13.9–19.3) | <0.001 |
Family history of cardiovascular diseases | 5.6 (4.9–6.6) | 10.2 (8.0–12.9) | <0.001 |
Smoking | 6.3 (5.5–7.2) | 8.5 (5.5–13.2) | 0.196 |
Hypertension | 3.4 (2.8–4.2) | 14.9 (12.6–17.5) | <0.001 |
Diabetes Mellitus | 4.0 (3.4–4.8) | 22.9 (18.9–27.6) | <0.001 |
High total cholesterol | 3.8 (3.1–4.7) | 11.9 (10.1–14.0) | <0.001 |
Low HDL cholesterol | 6.2 (5.2–7.3) | 6.9 (5.7–8.5) | 0.367 |
Incidence density per 1000 person-years among participants with at least one year of follow-up (2889 men and 3803 women).
Definition of risk factors is according to the Adult Treatment Panel III.
Based on Log Rank test for equality of event free survival between groups.