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. 2014 Aug 27;9(8):e105804. doi: 10.1371/journal.pone.0105804

Table 2. Incidence density (95% CI)a for coronary heart disease regarding risk factors at baseline.

Risk factorb Risk factor – Risk factor + P-Valuec
Men
 High risk age 4.2 (3.2–5.4) 19.5 (17.3–22.0) <0.001
 Family history of cardiovascular diseases 11.4 (10.2–12.9) 14.5 (11.1–18.9) 0.107
 Smoking 10.4 (8.9–12.2) 13.7 (11.7–15.9) 0.012
 Hypertension 8.8 (7.6–10.1) 23.2 (19.6–27.5) <0.001
 Diabetes Mellitus 9.6 (8.4–10.9) 31.4 (25.5–38.7) <0.001
 High total cholesterol 9.7 (8.5–11.1) 19.5 (16.2–23.4) <0.001
 Low HDL cholesterol 10.9 (9.0–13.3) 12.4 (10.8–14.1) 0.283
Women
 High risk age 3.3 (2.7–4.0) 16.4 (13.9–19.3) <0.001
 Family history of cardiovascular diseases 5.6 (4.9–6.6) 10.2 (8.0–12.9) <0.001
 Smoking 6.3 (5.5–7.2) 8.5 (5.5–13.2) 0.196
 Hypertension 3.4 (2.8–4.2) 14.9 (12.6–17.5) <0.001
 Diabetes Mellitus 4.0 (3.4–4.8) 22.9 (18.9–27.6) <0.001
 High total cholesterol 3.8 (3.1–4.7) 11.9 (10.1–14.0) <0.001
 Low HDL cholesterol 6.2 (5.2–7.3) 6.9 (5.7–8.5) 0.367
a

Incidence density per 1000 person-years among participants with at least one year of follow-up (2889 men and 3803 women).

b

Definition of risk factors is according to the Adult Treatment Panel III.

c

Based on Log Rank test for equality of event free survival between groups.