. Author manuscript; available in PMC: 2015 Jul 1.

Published in final edited form as: J Acquir Immune Defic Syndr. 2014 Jul 1;66(3):256–264. doi: 10.1097/QAI.0000000000000163

TABLE 2.

Effects for all cytokines significantly associated with cocaine use determined by the WLCM biostatistical model

Cytokine	Effect (p value)
	AT-VISIT	UPTO-VISIT	ALL VISIT
Eotaxin	25.93 (0.0336)	—	—
GM-CSF	—	—	8.74 (0.0437)
IL-10	—	—	29.07 (0.0208)
IL-4	14.25 (0.0021)*	11.19 (0.0261)	—
Th2 panel	—	27.99 (0.0364)	32.83 (0.0266)

The effect signifies the effect cocaine has on the value of each cytokine. A minus sign in front of the effect value denotes that the drug has a negative effect on the value of the cytokine (downregulation), while no sign in front of the effect value denotes that the drug has a positive effect on the value of the cytokine (upregulation). A asterisk signifies the correlation was significant when corrected for multiple testing (Benjamini-Hochberg). GM-CSF, granulocyte-macrophage colony-stimulating factor; IL, interleukin; WLCM, weighted linear contribution model.