Fig. 2.

Effects of fucoidan in the SE reconstruction. (A) Photographs of skin equivalents (SEs) in 24-mm transwell culture after 12 days of SE reconstruction. (B) SE sections were stained for H&E, PCNA, p63, α6-integrin, β1-integrin, type I collagen, elastin, and fibronectin. Each experiment was repeated independently three times, and representative results are shown. Original magnification, ×400. (C) PCNA, p63, and α6-integrin intensities were measured as described in 'Materials and Methods.' ^*p<0.01 compared to the control model.