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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Cell Microbiol. 2014 May 1;16(9):1391–1404. doi: 10.1111/cmi.12299

Figure 10.

Figure 10

Effect of GSK3β and NF-κβ inhibitors on Cdt-induced cytokine release. THP-1 derived macrophages were pre-exposed to LiCl, SB216763, GSK X inhibitor, GSK XII inhibitor, GSK XV inhibitor or Bay11–7082 (50 µM) for 30 min followed by the addition of Cdt (50 ng/ml). Twenty-four hr later supernatants were harvested and analyzed for TNFα by ELISA. Results are the mean ± SEM of three experiments. Asterisk indicates statistical significance (p<0.05) when compared to cells exposed to Cdt alone.