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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Cell Microbiol. 2014 Jun 2;16(9):1441–1455. doi: 10.1111/cmi.12305

Fig. 1. The β1 integrin in epithelial cells contributes to the IL-8 response to multiple bacterial pathogens.

Fig. 1

Panels: (A–C) INT 407 cells were transfected with either siRNA specific for the β1 integrin or scrambled (Scrm) siRNA. The cells were then infected with C. jejuni, H. pylori, or S. Typhimurium. Secreted IL-8 levels were determined by ELISA following 24 hr (C. jejuni) or 5 hr (H. pylori and S. Typhimurium) incubations. Non-transfected cells infected with each bacteria served as a positive control and untreated uninfected cells served as a negative control. (D) The efficiency of the β1 integrin knockdown was tested by immunoblot analysis of cell lysates, with actin serving as a loading control.