Figure 6. Tir-mediated actin assembly by C. rodentium (Φstx_2dact) promotes intestinal damage.

H&E stained intestinal sections of mice infected with the designated strain, taken at ten days post-infection, are shown at 200x magnification (top row). Bottom row shows a higher magnification of the designated square in the image above. Arrowheads indicate areas of inflammation, arrows indicate areas of goblet cells, and asterisks indicate areas of mucosal surface destruction and necrosis. Scale is 50 μm.