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. Author manuscript; available in PMC: 2015 Feb 1.
Published in final edited form as: J Antibiot (Tokyo). 2014 Apr 16;67(8):549–553. doi: 10.1038/ja.2014.36

Figure 2. Kinetics of anthracimycin activity against USA300 MRSA (strain TCH1516).

Figure 2

(a) Time-kill kinetics of anthracimycin at 1x, 5x, 10x, or 20x its MIC (MIC = 0.125 mg/L) during 24 hour incubation. (Note that the data points for the 5x, 10x, and 20x MIC anthracimycin are superimposed on the graph.) (b) Post-antibiotic effect of anthracimycin against USA300 MRSA (strain TCH1516) compared to vancomycin. The post-antibiotic effect was measured by incubating MRSA with anthracimycin or vancomycin for one hour (vertical line at 0 hr on the graph) and assessing 24 hour regrowth (viable bacteria) after washing the bacteria to remove the antibiotics. (Note that the data points for the 1x and 10x MIC vancomycin are nearly superimposed on the graph.)