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(A) Control neutrophils or lupus LDGs purified from whole blood and treated with or without chloroquine (CQ) were assessed for DNA externalization via Sytox assay. Immunofluorescent staining of these treated cells was used to quantify (B) NET production and (C) MPO, iNOS and p22 externalization on the NETs. (N=5/group; * p=0.01, *** p=0.0001, **** p<0.0001. Data are displayed as mean ± SEM.)
