Table 1. Demographic and clinic characteristics of healthy controls and SLE patients studied.
Statistically significant differences between groups are shown in bold; p < 0.05. Normally distributed variables are displayed as mean ± standard deviation. Skewed variables are displayed as median (IQR). ACE = Angiotensin Converting Enzyme, HDL = High Density Lipoprotein, LDL = Low Density Lipoprotein, MPO = Myeloperoxidase, ESR = Erythrocyte Sedimentation Rate, SLEDAI = Systemic Lupus Erythematosus Disease Activity Index
| Healthy Contro |
Lupus | |
|---|---|---|
| n=20 | n=40 | |
| Age (years) | 47.5 ± 10.9 | 48.2 ± 13.5 |
| Sex (males) | 10.0% (2) | 10.0% (4) |
| Body Mass Index (kg/m2) | 24.0 (6.6) | 27.8 (12.2) |
| Cholesterol (mg/dL) | 212.0 (58.0) | 150.0 (87.0) |
| Triglycerides (mg/dL) | 161.5 (89.0) | 124.5 (99.0) |
| HDL (mg/dL) | 57.5 (28.0) | 52.0 (18.5) |
| LDL (mg/dL) | 128.1 ± 29.7 | 92.9 ± 39.6 |
| ESR (mm/hr) | n/a | 13.0 (13.0) |
| C-Reactive Protein (mg/L) | n/a | 0.6 (0.7) |
| SLEDAI | 0 | 3.0 (6.0) |
| Steroid use | 0 | 42.5% (17) |
| Antimalarial use | 0 | 72.5% (29) |
| Statin Use | 0 | 22.5% (9) |
| Beta Blockers | 0 | 25.0% (10) |
| ACE inhibitor Use | 0 | 22.5% (9) |
| MPO (fmol/mL) | 326.7 (156.0) | 425.5 (212.0) |
| Cholesterol Efflux Capacity (%) |
9.2 ± 1.6 | 7.8 ± 1.5 |