Table 1.

Mass	Retention Time	Compound	Regulation in Lrp6 −/−	p	p (Corr)	Fold Change
85.09	5.19	Piperidine	down	1.17E-04	8.62E-04	−4.23
113.06	8.04	Creatinine	down	2.02E-04	1.02E-03	−1.75
119.057	6.32	Threonine	down	8.26E-05	7.43E-04	−1.72
131.07	8.03	Creatine	down	5.54E-03	1.40E-02	−1.99
131.095	5.19	Leucine/Isoleucine	down	7.44E-06	2.01E-04	−3.85
132.055	7.34	132.055@7.34	down	1.93E-02	4.11E-02	−1.98
133.039	9.37	Aspartic Acid	down	1.39E-04	8.65E-04	−1.34
135.038	8.04	Homocysteine	down	3.66E-05	5.93E-04	−1.79
136.039	2.05	Hypoxanthine	down	1.84E-03	6.23E-03	−4.94
137.045	7.45	p-Aminobenzoic acid	down	3.07E-04	1.38E-03	−1.83
146.106	12.38	Lysine	down	1.23E-02	2.93E-02	−1.68
149.052	5.22	Methionine	down	8.43E-04	3.10E-03	−2.34
153.051	8.03	153.051@8.03	down	1.32E-02	3.05E-02	−1.54
155.074	12.20	Histidine	down	2.15E-03	6.95E-03	−3.22
161.043	5.86	161.043@5.86	down	1.04E-04	8.44E-04	−3.76
168.087	12.37	168.087@12.37	down	1.98E-02	4.11E-02	−1.76
175.059	5.19	Dopamine [M+Na]+	down	3.20E-06	1.61E-04	−4.11
202.215	14.13	Spermine	up	1.93E-02	4.11E-02	2.62
203.116	8.48	Acetyicarnitine	down	7.53E-04	2.91E-03	−1.90
241.093	1.38	241.093@1.38	down	2.40E-03	7.47E-03	−2.37
241.277	1.90	241.277@1.90	up	4.43E-03	1.24E-02	1.97
256.14	9.38	256.14@9.38	down	1.90E-04	1.02E-03	−2.21
297.017	6.71	297.017@6.71	down	1.56E-03	5.49E-03	−2.14
307.085	5.79	Glutathione	down	2.68E-03	8.05E-03	−2.83
315.914	8.76	315.914@8.76	down	7.36E-05	7.43E-04	−3.56
398.139	13.10	S-adenosylmethionine	up	1.39E-02	3.14E-02	1.42
597.894	8.77	597.894@8.77	down	4.88E-03	1.27E-02	−1.88
695.873	8.76	695.873@8.76	down	3.52E-04	1.50E-03	−2.62
721.512	1.21	PE(20:5/15:0)	up	3.45E-03	9.99E-03	1.98
723.482	2.06	PE(18:4/18:1)	up	9.36E-03	2.30E-02	3.19