Table 1.
Expression of COX-2 protein in the gastric cancer and normal mucosa
| Variable | n |
COX-2 expression |
COX-2-positive rate (%) | χ2 | P | |
| - | + - +++ | |||||
| Tissue character | 12.191 | 0.000 | ||||
| Normal mucosa | 37 | 15 | 22 | 59.46 | ||
| Gastric cancer | 87 | 11 | 76 | 87.36 | ||
| Histologic type | 5.391 | 0.495 | ||||
| Papillary adenocarcinoma | 2 | 0 | 2 | 100.00 | ||
| Well-differentiated adenocarcinoma | 8 | 2 | 6 | 75.00 | ||
| Moderately-differentiated adenocarcinoma | 28 | 4 | 24 | 85.71 | ||
| Poorly-differentiated adenocarcinoma | 29 | 2 | 27 | 91.10 | ||
| Mucin adenocarcinoma | 12 | 0 | 12 | 100.00 | ||
| Signet-ring cell carcinoma | 5 | 1 | 4 | 80.00 | ||
| Undifferentiated carcinoma | 2 | 1 | 1 | 50.00 | ||
| Metastasis | 5.502 | 0.019 | ||||
| Negative | 21 | 6 | 15 | 71.43 | ||
| Positive | 66 | 5 | 61 | 92.42 | ||
| Depth of invasion | 6.315 | 0.043 | ||||
| Muscle invasion | 3 | 0 | 3 | 10.00 | ||
| Subserosa invasion | 68 | 20 | 48 | 70.59 | ||
| Serosa exposure invasion | 23 | 2 | 21 | 91.30 | ||
| Borrman type | 2.228 | 0.328 | ||||
| Borrman II | 7 | 0 | 7 | 100.00 | ||
| Borrman III | 85 | 9 | 76 | 89.41 | ||
| Borrman IV | 4 | 1 | 3 | 75.00 | ||