Table 1.
Effects of 5-FU and 5-FU + G-CSF administration on peritoneal defense mechanisms and systemic WBC counts. Figures are expressed as median (range)
| Control (n: 10) | 5-FU (n: 10) | 5-FU + G-CSF (n: 10) | |
| Bactericidal activity of peritoneal fluid MIC90 (bacteria/mL) | 17.90 (14.1-24.6) | 9.40 (6.2-13.8)a | 19.20 (14.3-26.8) |
| Phagocytic activity of PMNL | 56.3 (48.3-62.6) | 36 (25-51.6)a | 43.5 (37-58.6) |
| Cell counts in peritoneal fluid | 2000 (1500-2400) | 950 (600-1200)a | 1380 (800-1900) |
| Systemic WBC Counts | 9000 (4000-14000) | 2100 (1100-2600)a | 3400 (2200-4600) |
a
P < 0.05 vs control and 5-FU + G-CSF groups.